TGF-β1产品介绍：
转化生长因子β(transforming growth factor)家族由一类结构、功能相关的多肽生长因子亚家族组成，其中包括TGF-β、活化素(activin)、骨形态发生蛋白(BMP)、生长分化因子( GDF)等。TGF-β除了影响细胞的增殖、分化，还在胚胎发育、胞外基质形成、骨的形成和重建等方面起着重要作用。TGF-β家族成员广泛存在于从果蝇到人多种生物的各种组织中，对正常细胞、癌变细胞都有着显著作用。

TGF-β1产品特性：
? TGF-β1活性经过人源细胞鉴定，纯度高。
? 生物活性在人源293细胞经过SMAD实验鉴定The EC50为 0.1–1.0 ng/ml。
? TGF-β1产品经过SDS-PAGE 和HPLC双层鉴定纯度大于95%。

TGF-β1产品英文简述：
Members of TGF-family are multifunctional cytokines that regulate cell proliferation, growth, differentiation and migration as well as synthesis of the extracellular matrix. The three human isoforms, TGF- 1, 2, 3, signal through the same receptor and elicit similar biological responses. The release of biologically active TGF-isoform from a latent complex involves proteolytic processing of the complex. TGF-1 is the most abundant isoform secreted by almost all cell types. Human TGF-1 is a 25.0kDa protein with each subunit containing 112 amino acid residues, linked by a disulfide bond.

? Purity: Greater than 95% as determined by SDS-PAGE and HPLC analyses
? Biological Activity: The activity was determined by using a SMAD reporter gene assay in human 293 cells. The EC50 ranges from 0.1 – 1.0 ng/ml.
? For Research Use Only. Not for Use in Humans.

重庆市华雅干细胞技术有限公司

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